Chronic ailments of the structures of the respiratory system can develop under the influence of many factors: viral infections, bacteria and adverse weather conditions. Bronchial asthma, emphysema, bronchitis – they all belong to a whole category of diseases of the bronchopulmonary apparatus.
Pathologies of a chronic form are especially dangerous in the cold season, when there is a high risk of hypothermia, which leads to the development of acute respiratory viral infection. That is why people prone to such diseases should be prudent and attentive to their health.
Recently, asthma has begun to spread more and more actively, accompanied by dangerous symptoms: pulmonary edema, asthma attacks and increased formation of viscous sputum. Today, about 10% of the global population suffers from bronchial asthma. In the event of the first signs of the disease, you should immediately seek help from a medical institution. Proper https://ventolin-albuterol.com/ treatment will help initially eliminate the symptoms of bronchial obstructive disease and prevent the development of relapses.
Ventolin is a potent anti-asthma, used for therapeutic and prophylactic purposes in diseases of the bronchi and lungs, which are accompanied by bronchospastic syndrome. The medication is designed to stop asthma attacks, as well as suppress bronchospasm that occurs due to exposure to an allergen or high physical exertion. The medicine often becomes one of the components of the therapeutic complex with long-term treatment.
Release form, composition and packaging
Ventolin is marketed as an aerosol with a dispenser for inhalation therapy. It contains a specific liquid, which is made in the form of a suspension having a white or almost white color. An anti-asthma agent kit includes an aluminum aerosol can and a plastic inhalation device equipped with a protective cap and a metering mechanism.
The solution of the drug is based on the active component – salbutamol, as well as an auxiliary substance represented by the propellant. In drugstores, the medicine is dispensed only if there is a prescription from the attending physician.
Pharmacological properties
Aerosol for inhalation is a selective beta-adrenergic agonist, the main task of which is to eliminate bronchospasm in asthma. The medicine helps to increase the vital capacity of the lungs and protect the mucous membrane of the respiratory system from infections and other negative factors.
Salbutamol has a number of unique features. It produces a vasodilator effect, helps to improve sputum secretion and reduce the presence of potassium in the blood. In addition, as a hypolytic agent, it takes part in the activation of the ciliated epithelium, affects the breakdown of glycogen and the release of insulin.
After inhalation, salbutamol is instantly absorbed and spreads through the soft tissues and blood vessels. The effect of the drug occurs 5 minutes after use and can last for 5 hours. About 10% of the active substance forms a bond with plasma albumin.
A small part of the active substance (10-20%) enters the lower respiratory tract and undergoes the absorption process, distributed in the structures of the lungs and blood. The bulk of the drug is retained in the oropharynx and, after ingestion, is metabolized in the human liver. During biotransformation, salbutamol forms phenolic sulfate, which is excreted in the urine and in small amounts with feces.
Indications for starting Ventolin
Aerosol for inhalation is recommended for use by patients with:
- prolonged inflammation of the bronchi;
- bronchial asthma;
- obstruction of the lungs.
The drug helps to suppress the clinical symptoms of bronchial asthma as quickly as possible. Its mechanism of action is:
- in the localization of seizures and exacerbations in severe form;
- in the prevention of bronchospastic syndrome during exercise or the manifestation of an allergic reaction;
- in maintaining the functions of the bronchopulmonary apparatus during prolonged combination therapy.
Instructions for use
Aerosol is intended for inhalation use. The dosage and administration schedule for each patient is assigned individually, since it depends on the complexity of the disease and its etiology. Compliance with the prescription of a doctor will eliminate the development of side effects, which often lead to negative consequences.
To localize a bronchial attack, it is worth observing the following dosage of Ventolin:
- for children over 2 years old – 100 mcg no more than 4 times a day;
- for adults – about 200 mcg with a frequency of administration 3-4 times a day.
With proactive therapy, the recommended dose of anti-asthma for children and adults is 200 mcg at least 4 times a day.
As a prophylaxis before the planned physical activity or relationship with an allergen, a bronchodilator in the recommended dose of salbutamol should be used:
- for children – 100 mcg;
- for adults – 200 mcg.
The procedure is carried out 15 minutes before the intended contact.
Before taking the drug or prolonged non-use, the health of the inhalation device should be checked. To do this, remove the protective cap, shake the aerosol and spray it several times into the air.
Admission during pregnancy and breastfeeding
Ventolin aerosol is extremely rarely prescribed for pregnant women. If it is necessary to use this drug, strict medical supervision is carried out by the medical staff on the well-being of the patient and the effect of salbutamol. Accurate data on the negative effects of the drug on the fetus has not been recorded.
In isolated cases, taking a bronchodilator led to the birth of babies with various defects: dystrophy of the upper and lower extremities or a cleft palate. It should be noted that the occurrence of these pathologies was facilitated by the administration of an anti-asthma agent with drugs of other pharmacological groups.
Women who are breastfeeding should be aware that salbutamol has the ability to pass into breast milk. However, information on the negative effect of the drug on the baby is missing. Despite this, in order to avoid consequences, lactation should be interrupted before starting inhalation therapy.
Contraindications
Ventolin is prohibited for use in the following cases:
- during pregnancy;
- in the lactation period;
- children under the age of 1.5 years;
- with increased sensitivity to salbutamol;
- persons with heart failure.
In addition, there are a number of diseases in the presence of which a bronchodilator should be used with extreme caution:
- glaucoma
- impaired renal function;
- thyrotoxicosis;
- coronary heart disease;
- liver failure;
- epilepsy;
- heart disease;
- diabetes mellitus;
- aortic stenosis;
- myocarditis.
Side effects
Patients who have contraindications to taking Ventolin may experience the side effect of its active and inactive substances, which is most often manifested by the following symptoms:
- a decrease in the concentration of potassium ions in plasma;
- migraine headaches;
- tremor;
- heart palpitations;
- irritation of the oral mucosa;
- muscle cramps.
There are also isolated cases where the negative effect of the drug became the cause of the development of an allergic reaction, arrhythmia, Quincke’s edema and paradoxical bronchospasm with increased wheezing.
Overdose
Taking an increased dose of salbutamol can cause increased side effects, accompanied by:
- tachycardia;
- low blood pressure;
- hypokalemia;
- nausea and vomiting
- headache;
- increased excitement;
- muscle tremor.
It is extremely rare that an overdose can cause hallucinations, convulsions, ventricular flutter, and expansion of peripheral vessels. To eliminate the above symptoms resort to the use of cardioselective beta-blockers.
Interaction with other medicines
Patients suffering from thyrotoxicosis should be careful with Ventolin with central nervous system stimulants in order to avoid enhancing the therapeutic effect of analeptics. During the course of therapy with a bronchodilator, it is necessary to completely eliminate the use of beta-adrenoreceptor blockers.
For combination therapy of asthma and lung disease, not only aerosol for inhalation, but also monoamine oxidase inhibitors can be used. Anticholinergics together with a bronchodilator can cause intraocular pressure.
Patients should avoid the simultaneous use of a drug based on salbutamol with xanthan, which increase the risk of developing heart rate, diuretics and glucocorticosteroids, which enhance the effect of hypoglycemic nature.
Special instructions
While taking anti-asthma, safety precautions must be observed. Therapy of diseases of the bronchopulmonary apparatus is carried out in several stages to establish an effective treatment regimen. With exacerbation of bronchial asthma, the use of complex therapy is possible, which implies joint administration with glucocorticosteroids. Ventolin can be used in pediatric practice. It is often prescribed for children over 2 years old.
With proactive therapy, it is worthwhile to regularly undergo a laboratory examination to determine the level of potassium in the blood plasma. In addition, in the absence of a therapeutic effect 3 hours after inhalation, it is necessary to immediately consult a doctor.
There is no information on the effect of anti-asthma on the psychomotor reaction and concentration when driving a vehicle or working with mechanisms.
Analogs
In Russian pharmacy chains, there is a huge selection of bronchodilators that have a similar structure and mechanism of action and, if necessary, can replace Ventolin.
Among the sought-after analogues, the functioning substance of which is salbutamol:
- Aloprol.
- Salamol-Eco Easy breathing.
- Volmax.
- Astalin.
- Ventilor.
- Salbutamol-Neo.
- Salgim.
- Nebutamol.
Terms and conditions of storage
To preserve the therapeutic properties of the aerosol suspension, the rules for its storage should be observed. Ventolin is recommended to be stored in a home medicine cabinet away from children, avoiding exposure to light and heat. Favorable temperature storage of the medicine varies from +8 to +30 ° C, and the relative humidity does not exceed 60%. The aerosol can is not heated, frozen, or punctured.
Series of release, date of manufacture and final use are indicated on a cardboard bundle. Shelf life is 2 years.
Reviews about the drug
People suffering from bronchial asthma are looking for effective means to eliminate the negative symptoms of the disease. Ventolin from the Russian manufacturer GlaxoSmithKline Trading is increasingly being discussed at medical forums.
Patients using a bronchodilator for symptomatic therapy, note its ability to instantly stop attacks, eliminating swelling of the bronchial mucosa. Also, participants in the discussions indicate the speed of the drug and the rarity of side effects.
Some people claim that aerosol is a hormone medication. However, doctors are in a hurry to dispel a false opinion and reassure people, assuring that the anti-asthma does not have a hormonal effect.